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This will be far from the first Cleopatra project to hit the screen, as the Egyptian ruler has been depicted in numerous projects throughout the decades. On the big screen, the most notable depictions of Cleopatra are arguably from Cecil B. DeMille’s 1943 film, in which she was played by Claudette Colbert. And of course, there’s also the 1963 film from director Joseph L. Mankiewicz, which saw Elizabeth Taylor play the lead role.